In this video, Dr. James Farley discusses the growing prevalence of neurodegenerative conditions such as Parkinson’s disease and Alzheimer’s disease and explores factors that may contribute to this increase. He examines the roles of lifestyle, environmental influences, sleep, and the brain’s ability to clear metabolic waste, while explaining why looking beyond genetics alone may provide a broader perspective on neurological health.

Dr. Farley also discusses the brain’s glymphatic and lymphatic clearance systems, the accumulation of proteins such as beta-amyloid, tau, and alpha-synuclein, and the importance of healthy sleep. He explains his health-promotion approach to neurodegeneration—focusing on understanding contributing factors, supporting healthy neurological function, and shifting the conversation from simply managing disease toward promoting and optimizing health.